2025
The impact of Duration of Untreated Psychosis on functioning and quality of life over one year of Coordinated Specialty Care (CSC)
Hazan H, Tayfur S, Zhou B, Li F, Gibbs-Dean T, Karmani S, Kline E, Ferrara M, Corbera S, Riley S, Sykes L, Tek C, Keshavan M, Srihari V. The impact of Duration of Untreated Psychosis on functioning and quality of life over one year of Coordinated Specialty Care (CSC). PLOS ONE 2025, 20: e0312740. PMID: 39928579, PMCID: PMC11809850, DOI: 10.1371/journal.pone.0312740.Peer-Reviewed Original ResearchConceptsCoordinated specialty careQuality of lifeDuration of untreated psychosisDUP groupWorld Health OrganizationYear of coordinated specialty careGeneralized linear modelConfidence intervalsBinary outcomesGlobal functioningDuration of untreated psychosis groupSymptom severityUntreated psychosisSpecialty careCSC programsImpact of duration of untreated psychosisFunctional gainsModel repeated measuresMixed model repeated measuresOdds ratioNo significant differenceLogit link functionStatus improvementContinuous outcomesSocial functioning
2024
The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction
Hazan H, Ferrara M, Riley S, Li F, Zhou B, Kline E, Gibbs-Dean T, Karmani S, Tayfur S, Tek C, Keshavan M, Srihari V. The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction. Schizophrenia Research 2024, 264: 457-461. PMID: 38266513, PMCID: PMC10923115, DOI: 10.1016/j.schres.2024.01.022.Peer-Reviewed Original ResearchConceptsCoordinated specialty careDuration of untreated psychosisImpact of early detectionEarly detectionEarly detection campaignsSpecialty careAdjustment scoresCampaign yearDetection campaignsMediation analysisEffects of EDRegression modelsCareUntreated psychosisPositive symptomsGAFPatientsSalutary effects
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