Publications

• Translocating gut pathobiont Enterococcus gallinarum induces T(H)17 and IgG3 anti-RNA-directed autoimmunity in mouse and human.Gronke K, Nguyen M, Fuhrmann H, Santamaria de Souza N, Schumacher J, Pereira MS, Löschberger U, Brinkhege A, Becker NJ, Yang Y, Sonnert N, Leopold S, Martin AL, von Münchow-Klein L, Pessoa Rodrigues C, Cansever D, Hallet R, Richter K, Schubert DA, Daniel GM, Dylus D, Forkel M, Schwinge D, Schramm C, Redanz S, Lassen KG, Manfredo Vieira S, Piali L, Palm NW, Bieniossek C, Kriegel MA. Sci Transl Med. 2025 Feb 5; 2025 Feb 5. PMID: 39908347.
• Lupus and inflammatory bowel disease share a common set of microbiome features distinct from other autoimmune disorders.Zhou H, Balint D, Shi Q, Vartanian T, Kriegel MA, Brito I. Ann Rheum Dis. 2025 Jan; 2025 Jan 2. PMID: 39874239.
• Correction: Network analysis of polymicrobial chronic wound infections in Masanga, Sierra Leone.Sandmann S, Nunes JV, Grobusch MP, Sesay M, Kriegel MA, Varghese J, Schaumburg F. BMC Infect Dis. 2023 May 25; 2023 May 25. PMID: 37231329.
• Translocating Lactobacillus torments tumors via tryptophan catabolism.Pereira MS, Kriegel MA. Cell. 2023 Apr 27. PMID: 37116468.
• Research article network analysis of polymicrobial chronic wound infections in Masanga, Sierra Leone.Sandmann S, Nunes JV, Grobusch MP, Sesay M, Kriegel MA, Varghese J, Schaumburg F. BMC Infect Dis. 2023 Apr 18; 2023 Apr 18. PMID: 37072717.
• Evolving concepts of host-pathobiont interactions in autoimmunity.Pereira MS, Kriegel MA. Curr Opin Immunol. 2023 Feb; 2022 Nov 25. PMID: 36444784.
• Subdoligranulum chews up joints: how a gut pathobiont can instigate arthritis.Kriegel MA. Trends Immunol. 2023 Jan; 2022 Dec 6. PMID: 36494272.
• Structural host immune-microbiota interactions.Brito IL, Kriegel MA. Curr Opin Struct Biol. 2022 Oct; 2022 Sep 2. PMID: 36063760.
• Within-host evolution of a gut pathobiont facilitates liver translocation.Yang Y, Nguyen M, Khetrapal V, Sonnert ND, Martin AL, Chen H, Kriegel MA, Palm NW. Nature. 2022 Jul; 2022 Jul 13. PMID: 35831502.
• [The role of the microbiome in lupus and antiphospholipid syndrome].Redanz S, Kriegel MA. Z Rheumatol. 2022 Jun; 2022 Apr 5. PMID: 35380248.
• Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions.Dehner CA, Ruff WE, Greiling T, Pereira MS, Redanz S, McNiff J, Girardi M, Kriegel MA. JID Innov. 2022 Mar; 2021 Dec 16. PMID: 35199089.
• Skin Deep: The Role of the Microbiota in Cutaneous Autoimmunity.Pereira MS, Redanz S, Kriegel MA. J Invest Dermatol. 2022 Mar; 2022 Jan 10. PMID: 35027173.
• [Still's syndrome-similarities and differences between the juvenile and adult forms].Regel A, Föll D, Kriegel MA. Z Rheumatol. 2022 Feb; 2021 Nov 4. PMID: 34735597.
• Efficacy of therapeutic fasting and plant-based diet in patients with rheumatoid arthritis (NutriFast): study protocol for a randomised controlled clinical trial.Hartmann AM, Dell'Oro M, Kessler CS, Schumann D, Steckhan N, Jeitler M, Fischer JM, Spoo M, Kriegel MA, Schneider JG, Häupl T, Kandil FI, Michalsen A, Koppold-Liebscher DA. BMJ Open. 2021 Aug 11; 2021 Aug 11. PMID: 34380725.
• Host-microbiota interactions in immune-mediated diseases.Ruff WE, Greiling TM, Kriegel MA. Nat Rev Microbiol. 2020 Sep; 2020 May 26. PMID: 32457482.
• Friend or foe? Lactobacillus in the context of autoimmune disease.Fine RL, Mubiru DL, Kriegel MA. Adv Immunol. 2020; 2020 Mar 19. PMID: 32327152.
• Mechanisms and consequences of gut commensal translocation in chronic diseases.Fine RL, Manfredo Vieira S, Gilmore MS, Kriegel MA. Gut Microbes. 2020; 2019 Jul 15. PMID: 31306081.
• Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity.Ruff WE, Dehner C, Kim WJ, Pagovich O, Aguiar CL, Yu AT, Roth AS, Vieira SM, Kriegel C, Adeniyi O, Mulla MJ, Abrahams VM, Kwok WW, Nussinov R, Erkan D, Goodman AL, Kriegel MA. Cell Host Microbe. 2019 Jul 10; 2019 Jun 18. PMID: 31227334.
• The microbiome in systemic autoimmune disease: mechanistic insights from recent studies.Dehner C, Fine R, Kriegel MA. Curr Opin Rheumatol. 2019 Mar. PMID: 30624285.
• A Diet-Sensitive Commensal Lactobacillus Strain Mediates TLR7-Dependent Systemic Autoimmunity.Zegarra-Ruiz DF, El Beidaq A, Iñiguez AJ, Lubrano Di Ricco M, Manfredo Vieira S, Ruff WE, Mubiru D, Fine RL, Sterpka J, Greiling TM, Dehner C, Kriegel MA. Cell Host Microbe. 2019 Jan 9; 2018 Dec 20. PMID: 30581114.
• Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus.Greiling TM, Dehner C, Chen X, Hughes K, Iñiguez AJ, Boccitto M, Ruiz DZ, Renfroe SC, Vieira SM, Ruff WE, Sim S, Kriegel C, Glanternik J, Chen X, Girardi M, Degnan P, Costenbader KH, Goodman AL, Wolin SL, Kriegel MA. Sci Transl Med. 2018 Mar 28. PMID: 29593104.
• Translocation of a gut pathobiont drives autoimmunity in mice and humans.Manfredo Vieira S, Hiltensperger M, Kumar V, Zegarra-Ruiz D, Dehner C, Khan N, Costa FRC, Tiniakou E, Greiling T, Ruff W, Barbieri A, Kriegel C, Mehta SS, Knight JR, Jain D, Goodman AL, Kriegel MA. Science. 2018 Mar 9. PMID: 29590047.
• Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury.Bertacco A, Dehner CA, Caturegli G, D'Amico F, Morotti R, Rodriguez MI, Mulligan DC, Kriegel MA, Geibel JP. Front Physiol. 2017; 2017 Dec 19. PMID: 29311987.
• Self or non-self? The multifaceted role of the microbiota in immune-mediated diseases.Kriegel MA. Clin Immunol. 2015 Aug; 2015 May 21. PMID: 26003838.
• Autoimmune host-microbiota interactions at barrier sites and beyond.Ruff WE, Kriegel MA. Trends Mol Med. 2015 Apr; 2015 Mar 11. PMID: 25771098.
• The role of the gut microbiota in the pathogenesis of antiphospholipid syndrome.Ruff WE, Vieira SM, Kriegel MA. Curr Rheumatol Rep. 2015 Jan. PMID: 25475595.
• Diet, microbiota and autoimmune diseases.Vieira SM, Pagovich OE, Kriegel MA. Lupus. 2014 May. PMID: 24763536.
• Sex-specific environmental influences on the development of autoimmune diseases.Tiniakou E, Costenbader KH, Kriegel MA. Clin Immunol. 2013 Nov; 2013 Feb 28. PMID: 23507400.
• Emerging therapies for systemic lupus erythematosus--focus on targeting interferon-alpha.Lichtman EI, Helfgott SM, Kriegel MA. Clin Immunol. 2012 Jun; 2012 Apr 6. PMID: 22525889.
• Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c+ CD11b+ dendritic cells.Kriegel MA, Rathinam C, Flavell RA. Proc Natl Acad Sci U S A. 2012 Feb 28; 2012 Feb 10. PMID: 22328150.
• Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice.Kriegel MA, Sefik E, Hill JA, Wu HJ, Benoist C, Mathis D. Proc Natl Acad Sci U S A. 2011 Jul 12; 2011 Jun 27. PMID: 21709219.
• Does vitamin D affect risk of developing autoimmune disease?: a systematic review.Kriegel MA, Manson JE, Costenbader KH. Semin Arthritis Rheum. 2011 Jun; 2010 Nov 2. PMID: 21047669.
• E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance.Kriegel MA, Rathinam C, Flavell RA. Proc Natl Acad Sci U S A. 2009 Sep 29; 2009 Sep 17. PMID: 19805371.
• Sterile empyematous pleural effusion in a patient with systemic lupus erythematosus: a diagnostic challenge.Kriegel MA, Van Beek C, Mostaghimi A, Kyttaris VC. Lupus. 2009 Jun. PMID: 19433457.
• Anti-HLA-DR-triggered monocytes mediate in vitro T cell anergy.Kriegel MA, Adam-Klages S, Gabler C, Blank N, Schiller M, Scheidig C, Kalden JR, Lorenz HM. Int Immunol. 2008 Apr; 2008 Feb 28. PMID: 18310062.
• Interleukin-4 supports interleukin-12-induced proliferation and interferon-gamma secretion in human activated lymphoblasts and T helper type 1 cells.Kriegel MA, Tretter T, Blank N, Schiller M, Gabler C, Winkler S, Kalden JR, Lorenz HM. Immunology. 2006 Sep; 2006 Jun 6. PMID: 16762027.
• Transforming growth factor-beta: recent advances on its role in immune tolerance.Kriegel MA, Li MO, Sanjabi S, Wan YY, Flavell RA. Curr Rheumatol Rep. 2006 Apr. PMID: 16569373.
• Adrenal and gonadal hormone variations during a febrile attack in a woman with tumor necrosis factor receptor-associated periodic syndrome.Straub RH, Härle P, Kriegel M, Schölmerich J, Lorenz HM. J Clin Endocrinol Metab. 2005 Oct; 2005 Jul 19. PMID: 16030167.
• Lambert-Eaton myasthenic syndrome and undifferentiated connective tissue disease in a patient carrying the 8.1 ancestral haplotype.Kriegel MA, Kalden JR, Lorenz HM. Ann Rheum Dis. 2005 Jan. PMID: 15608326.
• Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II.Kriegel MA, Lohmann T, Gabler C, Blank N, Kalden JR, Lorenz HM. J Exp Med. 2004 May 3; 2004 Apr 26. PMID: 15117972.
• Tumor necrosis factor receptor-associated periodic syndrome characterized by a mutation affecting the cleavage site of the receptor: implications for pathogenesis.Kriegel MA, Hüffmeier U, Scherb E, Scheidig C, Geiler T, Kalden JR, Reis A, Lorenz HM. Arthritis Rheum. 2003 Aug. PMID: 12905494.
• A fast, simple and sensitive method for the detection and quantification of detergent-resistant membranes.Blank N, Gabler C, Schiller M, Kriegel M, Kalden JR, Lorenz HM. J Immunol Methods. 2002 Dec 20. PMID: 12445726.
• CD45 tyrosine phosphatase controls common gamma-chain cytokine-mediated STAT and extracellular signal-related kinase phosphorylation in activated human lymphoblasts: inhibition of proliferation without induction of apoptosis.Blank N, Kriegel M, Hieronymus T, Geiler T, Winkler S, Kalden JR, Lorenz HM. J Immunol. 2001 May 15. PMID: 11342620.