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Michael Grome, a postdoctoral associate in molecular, cellular, and developmental biology at Yale and first author of the study, likened codons to three-letter words within a sentence in the genetic recipe for life.
“A lot of these words are equivalent, or synonymous,” Grome said. “We set out to add more ingredients for building proteins, so we took three of these words for ‘stop’ and made them one. Two words were removed, then we re-engineered the cell so they were ‘freed’ for new function. We then engineered a cell that recognized the word to say something new, to represent a new ingredient.”
- September 13, 2023
Scientists reveal the 3D architecture and mechanism of mechanosensory corpuscles, a group of cells that act as a touch detector.
- February 23, 2023Source: Connecticut Academy of Science and Engineering
East Hartford, CT —The Connecticut Academy of Science and Engineering (CASE) announces the election of 35 of Connecticut’s leading experts in science, technology, engineering, mathematics, and medicine to membership in the Academy. The new members will be introduced at the Academy’s 48th Annual Meeting and Dinner to be held at the Woodwinds in Branford on May 24, 2023.
- January 17, 2022
Enhanced FIB-SEM has enabled discoveries in tissue biology, cell biology, and the connectome—the system of neural pathways in the brain. Recently, it enabled an open-access high-resolution 3D atlas of whole cells and tissues, from cancer and immune cells to mouse pancreatic islets and Drosophila neural tissues.