GABAergic disinhibition from the BNST to PNOCARC neurons promotes HFD-induced hyperphagia
Sotelo-Hitschfeld T, Minère M, Klemm P, Borgmann D, Wnuk-Lipinski D, Jais A, Jia X, Corneliussen S, Kloppenburg P, Fenselau H, Brüning J. GABAergic disinhibition from the BNST to PNOCARC neurons promotes HFD-induced hyperphagia. Cell Reports 2024, 43: 114343. PMID: 38865247, DOI: 10.1016/j.celrep.2024.114343.Peer-Reviewed Original ResearchInhibition of POMC neuronsGamma-aminobutyric acidPOMC neuronsArcuate nucleusBed nucleus of the stria terminalisHFD feedingGABAergic disinhibitionAnorexic responseBed nucleusRabies tracingInhibitory inputsStria terminalisObesity developmentNeuronal activityNeuronal circuitsCircuit mappingNeuronsHyperphagiaHFDCaloric contentBNSTTerminalisObesityMicePOMC
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