2024
Estimating pneumococcal carriage dynamics in adults living with HIV in a mature infant pneumococcal conjugate vaccine programme in Malawi, a modelling study
Phiri J, Sibale L, Mlongoti L, Mitole N, Kusakala A, Khwiya M, Kayembe T, Lisimba E, Kapwata P, Malisita K, Chaguza C, Ferreira D, Thindwa D, Jambo K. Estimating pneumococcal carriage dynamics in adults living with HIV in a mature infant pneumococcal conjugate vaccine programme in Malawi, a modelling study. BMC Medicine 2024, 22: 419. PMID: 39334289, PMCID: PMC11438070, DOI: 10.1186/s12916-024-03631-5.Peer-Reviewed Original ResearchConceptsNon-PCV13 serotypesAntiretroviral therapyPneumococcal carriage prevalencePneumococcal carriageCarriage prevalenceHIV- adultsStudy groupCarriage acquisitionDetect pneumococcal carriageAntiretroviral therapy durationHuman immunodeficiency virusSocial economic statusPneumococcal conjugate vaccination programmeMultivariate longitudinal analysesPCV13 serotypesProlonged carriageImmunodeficiency virusMedian ageHIV individualsNasopharyngeal clearancePneumococcal serotypesALWHIVLatex agglutinationCulture microbiologyPoint prevalence
2022
Social mixing patterns relevant to infectious diseases spread by close contact in urban Blantyre, Malawi
Thindwa D, Jambo K, Ojal J, MacPherson P, Dennis Phiri M, Pinsent A, Khundi M, Chiume L, Gallagher K, Heyderman R, Corbett E, French N, Flasche S. Social mixing patterns relevant to infectious diseases spread by close contact in urban Blantyre, Malawi. Epidemics 2022, 40: 100590. PMID: 35691100, PMCID: PMC9176177, DOI: 10.1016/j.epidem.2022.100590.Peer-Reviewed Original ResearchConceptsUrban BlantyreInfectious diseasesLow COVID-19 incidenceHIV-positive statusCOVID-19 circulationCOVID-19 incidenceCOVID-19 precautionsMedian ageHIV statusBinomial mixed effects modelsPandemic preparednessAge groupsClose contactSkin contactLow-income countriesNegative binomial mixed effects modelUrban MalawiMixed effects modelsSecondary school childrenUnemployed participantsTransmission dynamicsContact reductionAdultsBehavioral changesSchool children
2021
Tuberculosis case notifications in Malawi have strong seasonal and weather-related trends
Kirolos A, Thindwa D, Khundi M, Burke R, Henrion M, Nakamura I, Divala T, Nliwasa M, Corbett E, MacPherson P. Tuberculosis case notifications in Malawi have strong seasonal and weather-related trends. Scientific Reports 2021, 11: 4621. PMID: 33633272, PMCID: PMC7907065, DOI: 10.1038/s41598-021-84124-w.Peer-Reviewed Original Research
2017
The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys
Darton TC, Meiring JE, Tonks S, Khan MA, Khanam F, Shakya M, Thindwa D, Baker S, Basnyat B, Clemens JD, Dougan G, Dolecek C, Dunstan SJ, Gordon MA, Heyderman RS, Holt KE, Pitzer VE, Qadri F, Zaman K, Pollard AJ. The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys. BMJ Open 2017, 7: e016283. PMID: 28674145, PMCID: PMC5726077, DOI: 10.1136/bmjopen-2017-016283.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBangladeshCarrier StateCensusesChildChild, PreschoolCost of IllnessFemaleHealth ResourcesHumansIncidenceInfantInfant, NewbornMalawiMaleModels, TheoreticalNepalPatient Acceptance of Health CarePopulation SurveillanceResearch DesignSeroepidemiologic StudiesSurveys and QuestionnairesTyphoid FeverConceptsEnteric feverResearch Ethics CommitteeOxford Tropical Research Ethics CommitteeMedicine Research Ethics CommitteeAge-stratified serosurveyEnteric fever casesEthics CommitteeFebrile illness episodesHealthcare utilisation surveysPassive surveillanceNepal Health Research CouncilSecondary attack ratePopulation-based studyHealthcare-seeking behaviorGood clinical practiceDeclaration of HelsinkiHealth Research CouncilInstitutional review boardHousehold contactsPeer-reviewed journalsChronic carriageChronic carriersPrimary outcomeInternational peer-reviewed journalsStudy enrollment
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