Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression of atherosclerotic plaque
Zhang Y, Lu S, Qiu L, Qin M, Shan D, Xie L, Yi Y, Yu J. Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression of atherosclerotic plaque. Frontiers In Immunology 2025, 15: 1528475. PMID: 39896809, PMCID: PMC11781991, DOI: 10.3389/fimmu.2024.1528475.Peer-Reviewed Original ResearchTranscription factor enrichment analysisTranscription factorsGene OntologyExpressed genesSingle cell RNA-seq dataGene co-expression network analysisCo-expression network analysisGene Expression Omnibus (GEO) databaseRNA-seq analysisGene expression dataCell-cell communication analysisLigand-receptor pairsRNA-seqRegulate ubiquitinationExpression dataMIF signaling pathwaysIntegrated single-cellRNA sequencingEnrichment analysisTarget genesGenesTranscriptionZNF267Signaling pathwayMAPK pathway
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