AMPA Receptors Regulate Exocytosis and Insulin Release in Pancreatic β Cells
Wu Z, Zhu L, Zou N, Bombek L, Shao C, Wang N, Wang X, Liang L, Xia J, Rupnik M, Shen Y. AMPA Receptors Regulate Exocytosis and Insulin Release in Pancreatic β Cells. Traffic 2012, 13: 1124-1139. PMID: 22540213, DOI: 10.1111/j.1600-0854.2012.01373.x.Peer-Reviewed Original ResearchConceptsK(ATP) channelsGlutamate applicationB cellsInsulin releaseA-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptorIonotropic glutamate receptorsKnock-out miceDepolarization-induced exocytosisMouse B cellsInsulin-containing granulesPancreatic B-cellsGlutamate receptorsCytosolic calciumCytosolic cGMPAMPARAcid receptorsInsulin secretionInsulinoma cellsInsulinGlutamateMiceReceptorsExocytosisIGluRsRelease
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