Graft-Versus-Host-Disease Recruits Both Monocyte and Pre-Conventional Dendritic Cell-Derived Tissue Antigen Presenting Cells Independent Of CCR2 and CCR6
Morin-Zorman S, Wysocki C, Matte-Martone C, Juchem K, Tan H, Venkatesan S, Rothstein D, Lakkis F, Shlomchik W. Graft-Versus-Host-Disease Recruits Both Monocyte and Pre-Conventional Dendritic Cell-Derived Tissue Antigen Presenting Cells Independent Of CCR2 and CCR6. Blood 2013, 122: 4463. DOI: 10.1182/blood.v122.21.4463.4463.Peer-Reviewed Original ResearchAntigen presenting cellsDonor T cellsDendritic cellsT cellsGVHD miceDC populationsBlood monocytesAllogeneic hematopoietic stem cell transplantationAlloreactive donor T cellsHematopoietic stem cell transplantationMyeloid hematopoiesisInitial T cell activationRole of CCR2Role of CCR6Role of CX3CR1Stem cell transplantationSecondary lymphoid organsModels of inflammationWild-type BMSuppressor of inflammationWT T cellsT cell activationGraft-VersusGVHD lesionsGVHD reactions
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