2024
Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling
Ohashi Y, Protack C, Aoyagi Y, Gonzalez L, Thaxton C, Zhang W, Kano M, Bai H, Yatsula B, Alves R, Hoshina K, Schneider E, Long X, Perry R, Dardik A. Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling. Scientific Reports 2024, 14: 13287. PMID: 38858395, PMCID: PMC11164895, DOI: 10.1038/s41598-024-64075-8.Peer-Reviewed Original ResearchConceptsGene expression patternsArteriovenous fistula groupArteriovenous fistulaExpression patternsHeterogeneous gene expressionGene expression changesOutcomes of arteriovenous fistulaVenous remodelingArteriovenous fistula maturationPostoperative day 7Reduce patient morbidityRNA sequencingUpregulation of metabolismBioinformatics analysisGene expressionDownregulation of metabolismMetabolic pathwaysExpression changesGenesAVF maturationAVF remodelingFistula creationC57BL/6 miceClinical outcomesPatient morbidity
2023
Sex hormones impact early maturation and immune response in the arteriovenous fistula mouse model
Satam K, Ohashi Y, Thaxton C, Gonzalez L, Setia O, Bai H, Aoyagi Y, Xie Y, Zhang W, Yatsula B, Martin K, Cai Y, Dardik A. Sex hormones impact early maturation and immune response in the arteriovenous fistula mouse model. AJP Heart And Circulatory Physiology 2023, 325: h77-h88. PMID: 37145957, PMCID: PMC10243550, DOI: 10.1152/ajpheart.00049.2023.Peer-Reviewed Original ResearchConceptsIntact female miceAVF maturationSex hormonesT cellsFemale miceArteriovenous fistulaMale miceMouse modelHigher IL-10Arteriovenous fistula creationImmune cell recruitmentSex-specific therapiesHormone receptor signalingSex differencesHuman AVF maturationAVF surgeryMale patientsClinical outcomesFemale patientsFistula maturationIL-10C57BL/6 miceInferior outcomesVenous adaptationFistula creation
2015
Comparisons of financial and short-term outcomes between laparoscopic and open hepatectomy: benefits for patients and hospitals
Kawaguchi Y, Otsuka Y, Kaneko H, Nagai M, Nomura Y, Yamamoto M, Otani M, Ohashi Y, Sugawara K, Koike D, Ishida T, Kokudo N, Tanaka N. Comparisons of financial and short-term outcomes between laparoscopic and open hepatectomy: benefits for patients and hospitals. Surgery Today 2015, 46: 535-542. PMID: 26021453, DOI: 10.1007/s00595-015-1189-0.Peer-Reviewed Original ResearchConceptsLaparoscopic hepatectomyOpen hepatectomyShort-term outcomesTotal hospital chargesLH groupHospital stayPostoperative hospital stayHospital chargesReduced hospital stayBlood lossPostoperative complicationsMethodsThe subjectsInflow occlusionRetrospective analysisSurgical costsOperative timeDiagnosis Procedure CombinationPatientsHepatectomyProcedure CombinationHospitalStayOutcomesCost outcomesGroup
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