Does lower extremity fracture fixation technique influence neurologic outcomes in patients with traumatic brain injury? The EAST Brain vs. Bone multicenter trial
Ghneim M, Kufera J, Zhang A, Penaloza-Villalobos L, Swentek L, Watras J, Smith A, Hahn A, Mederos D, Dickhudt T, Laverick P, Cunningham K, Norwood S, Fernandez L, Jacobson L, Williams J, Lottenberg L, Azar F, Shillinglaw W, Slivinski A, Nahmias J, Donnelly M, Bala M, Egodage T, Zhu C, Udekwu P, Norton H, Dunn J, Baer R, McBride K, Santos A, Shrestha K, Metzner C, Murphy J, Schroeppel T, Stillman Z, O'Connor R, Johnson D, Berry C, Ratner M, Reynolds J, Humphrey M, Scott M, Hickman Z, Twelker K, Legister C, Glass N, Siebenburgen C, Palmer B, Semon G, Lieser M, McDonald H, Bugaev N, LeClair M, Stein D, Group T. Does lower extremity fracture fixation technique influence neurologic outcomes in patients with traumatic brain injury? The EAST Brain vs. Bone multicenter trial. Journal Of Trauma And Acute Care Surgery 2023, 95: 516-523. PMID: 37335182, DOI: 10.1097/ta.0000000000004095.Peer-Reviewed Original ResearchConceptsNeurologic outcomeFracture fixation techniquesIntramedullary nailingIMN groupTBI patientsGlasgow Coma Scale motor scoreHead Abbreviated Injury Scale scoreAbbreviated Injury Scale scoreFixation techniquesSevere lower extremity injuriesEx-fix groupRancho Los AmigosInjury Scale scoreProspective observational studyScale motor scoreLower extremity fracturesAge 18 yearsLower extremity injuriesTraumatic brain injuryMultivariable regression modelsHead AISORIF groupOperative interventionDefinitive managementExtremity fractures
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