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A new study led by Yale investigators demonstrated that patients with severe aortic stenosis treated with TAVR have comparable five-year outcomes to those treated with surgical aortic valve replacement (SAVR). The study was published in the Journal of the American College of Cardiology (JACC) on March 30, 2025, and was presented as a late-breaking study at the 2025 American College of Cardiology (ACC) Annual Scientific Session. Yale performed the first TAVR in Connecticut nearly fifteen years ago. Since then, Yale has continued to invest in research, people, and technology to bring TAVR and other minimally invasive procedures to more patients with valvular and structural heart disease.

Daniela Tirziu, PhD, recently received a promotion to senior research scientist (cardiovascular medicine) in July 2024. Tirziu joined Yale in 2008 and is now the associate director of academic research for the Yale Cardiovascular Research Group (YCRG), where she focuses on the design of clinical trials, the management of reporting and regulatory requirements, and the dissemination of the results of interventional cardiovascular devices. Tirziu started her career in basic science research, where her work advanced the understanding of cellular crosstalk in the heart.

The Department of Internal Medicine is pleased to welcome the following new staff, faculty, postdoctoral fellows, and postdoctoral associates who joined the team in March 2025.

A novel decentralized clinical trial found that Paxlovid was ineffective in alleviating Long COVID symptoms but underscored the importance of a patient-centered approach.

Michael Beasley, MD, assistant professor of medicine (cardiovascular medicine), and Nora Segar, MD, assistant clinical professor (general internal medicine) and director of palliative medicine at the Saint Raphael Campus of Yale New Haven Hospital, recently established a new outpatient clinic to provide dedicated palliative care for people with end-stage heart failure.

The Department of Internal Medicine announces its newest incoming class of residents for Match Day 2025.

WEDNESDAY, March 19, 2025 (HealthDay News) -- Elderly people benefit from taking medications to keep their blood pressure low, same as younger folks, a new study says. "The key question is, should blood pressure be lowered aggressively, or is a more moderate approach safer?” said Yale assistant professor of cardiology Yuan Lu.

Preprint server medRxiv played an essential role during the pandemic. Its founders are part of a new effort to guarantee the server’s long-term stability.

"These are patients that before we had these more innovative, less invasive approaches, the options were either a high-risk surgery or nothing, kind of continued medical management. (BATMAN) has really opened up a set of treatment avenues for patients that before were felt to just be too sick for traditional surgery," said Dr. Amit Vora, the director of the Transcatheter Mitral Valve program at Yale and one of the lead surgeons who helped perform the procedure in Connecticut for what is believed to be the first time.