Cenk Tek, MD
Professor of PsychiatryDownloadHi-Res Photo
Cards
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Director, Psychosis Program, CMHC
Contact Info
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Director, Psychosis Program, CMHC
Contact Info
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Director, Psychosis Program, CMHC
Contact Info
About
Copy Link
Titles
Professor of Psychiatry
Director, Psychosis Program, CMHC
Biography
Cenk Tek, MD, is a psychiatrist with a focus on treating individuals with psychotic disorders. He specializes in treating conditions such as schizophrenia and bipolar disorder, providing a comprehensive range of treatments that include medication management and psychosocial interventions designed to stabilize symptoms and promote long-term recovery.
Dr. Tek?s research involves exploring the most effective treatments for psychotic disorders. He has been involved in developing and refining early intervention services for individuals experiencing their first episode of psychosis, and he works on improving clinical outcomes for these patients.
Dr. Tek received his medical training from Hacettepe University Faculty of Medicine in Turkey. He completed his residency and psychiatry fellowship at Yale School of Medicine.
Appointments
Psychiatry
ProfessorPrimary
Other Departments & Organizations
- All Institutions
- Connecticut Mental Health Center
- Neuroscience Research Training Program (NRTP)
- Psychiatry
- Psychosis Program at Yale
- WHRY Pilot Project Program Investigators
- Women's Health Research at Yale
- Yale Medicine
- Yale New Haven Health System
- Yale Ventures
Education & Training
- Residency
- University of Maryland Medical System (2001)
- Internship
- Hacettepe University Medical School (1995)
- MD
- Hacettepe University Faculty of Medicine (1991)
- MD
- Hacettepe University Medical School (1991)
Research
Copy Link
Overview
Medical Research Interests
Diseases; Health Care; Memory; Obesity; Psychiatry; Psychiatry and Psychology; Schizophrenia
ORCID
0000-0002-3439-1914
Research at a Glance
Yale Co-Authors
Frequent collaborators of Cenk Tek's published research.
Publications Timeline
A big-picture view of Cenk Tek's research output by year.
Research Interests
Research topics Cenk Tek is interested in exploring.
Vinod H. Srihari, MD
Fangyong Li, MS, MPH
Hadar Hazan, PhD
Maria Ferrara, MD
Sarah Riley, MD
Sinan Guloksuz, MD, PhD
34Publications
859Citations
Publications
2025
Enhancing Coordinated Specialty Care Through Early Detection: Impact of Reduced Duration of Untreated Psychosis
Hazan H, Ferrara M, Zhou B, Li F, Imetovski S, Sykes L, Pollard J, Cahill J, Gibbs-Dean T, Corbera S, Karmani S, Riley S, Tayfur S, Tek C, Keshavan M, Srihari V. Enhancing Coordinated Specialty Care Through Early Detection: Impact of Reduced Duration of Untreated Psychosis. Schizophrenia Bulletin 2025, sbaf044. PMID: 40339151, DOI: 10.1093/schbul/sbaf044.Peer-Reviewed Original ResearchCitationsConceptsDuration of untreated psychosisFirst-episode psychosisCoordinated Specialty CareUntreated psychosisMediation analysisShorter duration of untreated psychosisFirst-episode psychosis patientsEarly interventionEarly psychosisBenefits of early interventionPsychosisGAFFunctional outcomesGlobal assessmentEarly detection campaignsSpecialty careIntake processRecovery outcomesSpecial treatmentQuality of lifeStreamlining referralsFunctional recoveryScoresPatientsInterventionInsight and Its Trajectory: Predicting the Risk of Psychiatric Hospitalizations Among First-Episode Psychosis During the First Year of Coordinated Specialty Care
Hazan H, Ferrara M, Gibbs-Dean T, Tayfur S, Corbera S, Karmani S, Song Z, Li F, Vlachos I, Selakovic M, Tek C, Srihari V. Insight and Its Trajectory: Predicting the Risk of Psychiatric Hospitalizations Among First-Episode Psychosis During the First Year of Coordinated Specialty Care. Schizophrenia Bulletin 2025, sbaf019. PMID: 40227145, DOI: 10.1093/schbul/sbaf019.Peer-Reviewed Original ResearchConceptsCoordinated Specialty CareFirst-episode psychosisBaseline insightRisk of psychiatric hospitalizationFirst-episodeEarly psychosisInsight groupLength of stayPsychiatric hospitalSpecialty carePsychosisLongitudinal trajectoriesGreater reductionsHospital outcomesHigh-low-highPredicting clinical improvementHospital dataModifiable factorsMonths pre-ParticipantsHospitalization riskClinical improvementRecovery trajectoriesReduce hospitalizationsBaselineThe STEP Learning Collaborative: A statewide Learning Healthcare System (LHS) for first episode psychosis
Yoviene Sykes L, Levine N, Tayfur S, Gibbs-Dean T, Hazan H, Imetovski S, James J, Karmani S, Mathis W, Markovich P, Purushothaman D, Riley S, Tek C, Veillette C, Cahill J, Giard J, Marracino A, Barrette K, Bozak S, Gregory F, McDermott G, Srihari V. The STEP Learning Collaborative: A statewide Learning Healthcare System (LHS) for first episode psychosis. Schizophrenia Research 2025, 278: 96-108. PMID: 40132282, PMCID: PMC11981821, DOI: 10.1016/j.schres.2025.03.029.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsLearning healthcare systemLearning CollaborativeHealthcare systemSchizophrenia spectrum disordersPopulation health outcomesLearning health systemSystems of careCare modelHigh-quality treatmentStage of illnessHealth outcomesHealth systemWorkforce developmentDuration of untreated psychosisStatewide systemEarly stages of illnessEarly psychosisWorkforce readinessStrengthening integrationPolicy advocacyLeverage informaticsCareEpisode psychosisStakeholder engagementUntreated psychosisDeep multimodal representations and classification of first-episode psychosis via live face processing
Singh R, Zhang Y, Bhaskar D, Srihari V, Tek C, Zhang X, Noah J, Krishnaswamy S, Hirsch J. Deep multimodal representations and classification of first-episode psychosis via live face processing. Frontiers In Psychiatry 2025, 16: 1518762. PMID: 40134976, PMCID: PMC11934110, DOI: 10.3389/fpsyt.2025.1518762.Peer-Reviewed Original ResearchAltmetricConceptsFirst-episode psychosisPositive and Negative Syndrome ScaleFunctional Near-Infrared SpectroscopyGlobal Assessment of FunctioningEarly psychosisNeural correlates of social cognitionFirst-episode psychosis individualsNegative Syndrome ScaleBehavior recordsAssessment of functioningSevere psychiatric disordersSyndrome ScaleFace processingPsychosis symptomsNeural underpinningsSocial cognitionNeural correlatesPsychiatric disordersBrain activitySocial difficultiesNeurophysiological dysfunctionPsychosisNeural characteristicsMultimodal representationsAcquisition paradigmThe impact of Duration of Untreated Psychosis on functioning and quality of life over one year of Coordinated Specialty Care (CSC)
Hazan H, Tayfur S, Zhou B, Li F, Gibbs-Dean T, Karmani S, Kline E, Ferrara M, Corbera S, Riley S, Sykes L, Tek C, Keshavan M, Srihari V. The impact of Duration of Untreated Psychosis on functioning and quality of life over one year of Coordinated Specialty Care (CSC). PLOS ONE 2025, 20: e0312740. PMID: 39928579, PMCID: PMC11809850, DOI: 10.1371/journal.pone.0312740.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsCoordinated Specialty CareQuality of lifeDuration of untreated psychosisDUP groupWorld Health OrganizationYear of coordinated specialty careGeneralized linear modelConfidence intervalsBinary outcomesGlobal functioningDuration of untreated psychosis groupSymptom severityUntreated psychosisSpecialty careCSC programsImpact of duration of untreated psychosisFunctional gainsModel repeated measuresMixed model repeated measuresOdds ratioNo significant differenceLogit link functionStatus improvementContinuous outcomesSocial functioningInsight and suicidality in first-episode psychosis: The mediating role of depression
Tayfur S, Song Z, Li F, Hazan H, Gibbs-Dean T, Purushothaman D, Karmani S, Terashima J, Tek C, Srihari V. Insight and suicidality in first-episode psychosis: The mediating role of depression. Schizophrenia Research 2025, 275: 189-195. PMID: 39754935, DOI: 10.1016/j.schres.2024.12.013.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsFirst-episode psychosisPredictors of suicideCoordinated Specialty CareTreatment of depressionPersistence of depressionEffects of depressionSuicide attemptsMediation analysisPrevent SuicideDepressionSuicideImpact suicidePsychosisTargeted interventionsLongitudinal cohort studyEarly treatment stageParticipantsSignificant predictorsImproving clinical outcomesRegression analysisSpecialty careClinical outcomesCohort studyRelationshipMonths
2024
Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial
Grilo C, Ivezaj V, Tek C, Yurkow S, Wiedemann A, Gueorguieva R. Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial. American Journal Of Psychiatry 2024, 182: 209-218. PMID: 39659158, PMCID: PMC11786997, DOI: 10.1176/appi.ajp.20230982.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCognitive-behavioral therapyBinge-eating disorderEffectiveness of cognitive-behavioral therapyBinge-eating remission ratesEating-disorder psychopathologyCognitive behavioral therapyEvidence-based treatmentsRemission ratePercent weight lossHigher remission ratesBinge-eating frequencyBehavioral therapyPosttreatment assessmentLisdexamfetamineRandomized Controlled TrialsHeightened ratesCostly public health problemIntention-to-treat ratesFunctional impairmentWeight lossControlled TrialsDisordersPosttreatmentIndividualized treatmentMixed modelsLisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial
Grilo C, Ivezaj V, Yurkow S, Tek C, Wiedemann A, Gueorguieva R. Lisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2024, 54: 3334-3344. PMID: 39258475, PMCID: PMC11496227, DOI: 10.1017/s003329172400148x.Peer-Reviewed Original ResearchCitationsAltmetricConceptsEating-disorder psychopathologyBinge-eating disorderMaintenance treatmentAcute treatmentBinge-eating remission ratesCognitive-behavioral therapyEfficacy of lisdexamfetamineSignificant weight gainDouble-blind placebo-controlled trialAcute respondersLisdexamfetamine treatmentPsychopathological outcomesPosttreatment assessmentLisdexamfetaminePlacebo-controlled trialRandomized double-blind placebo-controlled trialSingle-site trialAssociated with significant weight lossPsychopathologyBinge-eatingRemission rateWeight lossPlaceboRelapse rateControl researchThe impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction
Hazan H, Ferrara M, Riley S, Li F, Zhou B, Kline E, Gibbs-Dean T, Karmani S, Tayfur S, Tek C, Keshavan M, Srihari V. The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction. Schizophrenia Research 2024, 264: 457-461. PMID: 38266513, PMCID: PMC10923115, DOI: 10.1016/j.schres.2024.01.022.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCoordinated Specialty CareDuration of untreated psychosisImpact of early detectionEarly detectionEarly detection campaignsSpecialty careAdjustment scoresCampaign yearDetection campaignsMediation analysisEffects of EDRegression modelsCareUntreated psychosisPositive symptomsGAFPatientsSalutary effects
2023
The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service
Ferrara M, Guloksuz S, Hazan H, Li F, Tek C, Sykes L, Riley S, Keshavan M, Srihari V. The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service. Schizophrenia Research 2023, 260: 198-204. PMID: 37688984, DOI: 10.1016/j.schres.2023.08.005.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsFirst-episode psychosis servicesLength of stayUntreated psychosisPsychiatric hospitalizationFirst-episode servicesDuration of hospitalizationIncidence rate ratiosNon-affective psychosisNew Haven areaPoisson regression modelsPatient characteristicsHospitalization ratesRecent onsetMedical recordsHospitalizationEffect of durationNegative binomial regressionSpecialized treatmentPsychosisRate ratioBinomial regressionAdmissionDUPEnrollmentFirst year
Clinical Trials
Current Trials
Treatments to Treat Loss-of-Control Eating and Improve Weight Outcomes after Bariatric Surgery
HIC ID2000029057RoleSub InvestigatorPrimary Completion Date11/30/2027Recruiting Participants
Clinical Care
Copy Link
Overview
Cenk Tek, MD, is a psychiatrist with a focus on treating individuals with psychotic disorders. He specializes in treating conditions such as schizophrenia and bipolar disorder, providing a comprehensive range of treatments that include medication management and psychosocial interventions designed to stabilize symptoms and promote long-term recovery.
Dr. Tek’s research involves exploring the most effective treatments for psychotic disorders. He has been involved in developing and refining early intervention services for individuals experiencing their first episode of psychosis, and he works on improving clinical outcomes for these patients.
Dr. Tek received his medical training from Hacettepe University Faculty of Medicine in Turkey. He completed his residency and psychiatry fellowship at Yale School of Medicine.
Clinical Specialties
Psychiatry
Board Certifications
Psychiatry
- Certification Organization
- AB of Psychiatry & Neurology
- Original Certification Date
- 2002
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileNews
Copy Link
News
- May 19, 2025
Understanding Social Disconnect in Psychosis: A New fNIRS Study at Yale
- December 11, 2024Source: The American Journal of Psychiatry
Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial
- October 24, 2024Source: Cambridge University Press
Lisdexamfetamine Maintenance Treatment for Binge-Eating Disorder Following Successful Treatments
- February 13, 2024Source: WNPR
Mindmap 2.0 on Connecticut Public Radio
Get In Touch
Copy Link
Contacts
Locations
Connecticut Mental Health Center
Academic Office
34 Park Street, Ste Rm. 267E
New Haven, CT 06519