About
Titles
Hospital Resident
Departments & Organizations
- All Institutions
Education & Training
- DMD
- Tufts University School of Dental Medicine (2021)
- BS
- Northeastern University, Health Science (2017)
Research
Publications
Featured Publications
Feasibility and benefits of computerized cognitive exercise to adults with chronic moderate-to-severe cognitive impairments following an acquired brain injury: A pilot study.
O'Neil-Pirozzi TM, Hsu H. Feasibility and benefits of computerized cognitive exercise to adults with chronic moderate-to-severe cognitive impairments following an acquired brain injury: A pilot study. Brain Injury 2016, 30: 1617-1625. PMID: 27680422, DOI: 10.1080/02699052.2016.1199906.Peer-Reviewed Original Research
2024
Phase 1b/2 Study of Orally Administered Pexidartinib in Combination with Radiation Therapy and Temozolomide in Patients with Newly Diagnosed Glioblastoma
Mendez J, Cohen A, Eckenstein M, Jensen R, Burt L, Salzman K, Chamberlain M, Hsu H, Hutchinson M, Iwamoto F, Ligon K, Mrugala M, Pelayo M, Plotkin S, Puduvalli V, Raizer J, Reardon D, Sterba M, Walbert T, West B, Wong E, Zhang C, Colman H. Phase 1b/2 Study of Orally Administered Pexidartinib in Combination with Radiation Therapy and Temozolomide in Patients with Newly Diagnosed Glioblastoma. Neuro-Oncology Advances 2024, vdae202. DOI: 10.1093/noajnl/vdae202.Peer-Reviewed Original ResearchConceptsMedian overall survivalRadiation therapyAdjuvant TMZTumor microenvironmentRecommended phase 2 doseModified intention-to-treat populationIntention-to-treat populationPhase 1b/2 studyPhase 1b/2 trialPhase 2 doseProgression-free survivalNewly diagnosed glioblastomaInhibitor of CSF1RMultiple dose levelsPhase 2 patientsDose escalationMedian survivalDiagnosed GBMOverall survivalOpen-labelStudy regimensTreatment resistanceGlioma modelRP2DHistorical controls
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