Hung-Mo Lin
Professor of Anesthesiology and BiostatisticsCards
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Professor of Anesthesiology and Biostatistics
Biography
Meet Yale Center for Analytical Sciences' Hung-Mo Lin.
Last Updated on June 08, 2023.
Appointments
Anesthesiology a
ProfessorPrimaryBiostatistics
ProfessorSecondary
Other Departments & Organizations
Education & Training
- ScD
- Harvard University School of Public Health, Biostatistics
- MS
- Harvard University School of Public Health, Biostatistics
Research
Publications
2025
Ultrasound Gel versus Saline for Acoustic Coupling in Ultrasound-Guided Regional Anesthesia: A Randomized, Cross-Over, Simulation Study.
Burnett G, Bhavsar A, Hojsak S, Jeng C, Anderson M, Ouyang Y, Lin H, Park C. Ultrasound Gel versus Saline for Acoustic Coupling in Ultrasound-Guided Regional Anesthesia: A Randomized, Cross-Over, Simulation Study. Anesthesia & Analgesia 2025 PMID: 40408299, DOI: 10.1213/ane.0000000000007585.Peer-Reviewed Original ResearchComparison of Posterior Quadratus Lumborum Block vs Surgical Wound Infiltration in Patients Undergoing Bariatric Sleeve Gastrectomy Surgery
Shariat A, Kadakia R, Lin H, Egorova N, Jin S, Latmore M, Epstein J, Pai B.H P, Park K, Kini S, Bhatt H. Comparison of Posterior Quadratus Lumborum Block vs Surgical Wound Infiltration in Patients Undergoing Bariatric Sleeve Gastrectomy Surgery. Obesity Surgery 2025, 1-7. PMID: 40404913, DOI: 10.1007/s11695-025-07934-1.Peer-Reviewed Original ResearchPosterior quadratus lumborum blockLaparoscopic sleeve gastrectomySurgical wound infiltrationPostoperative opioid consumptionVAS pain scoresPostoperative day 1Quadratus lumborum blockWound infiltrationPain scoresRandomized pilot studyOpioid consumptionLocal anestheticsDay 1Decreased postoperative opioid consumptionVisual analog pain scorePostoperative VAS pain scoresInfiltration of local anestheticWound infiltration groupAnalog pain scoresASA 3 patientsPostoperative analgesic medicationPostoperative day 2Incidence of nauseaSleeve gastrectomy surgeryMorphine equivalentsOpioid Dose Variation in Cardiac Surgery: A Multicenter Study of Practice
Fisher C, Janda A, Zhao X, Deng Y, Bardia A, Yanez N, Burns M, Aziz M, Treggiari M, Mathis M, Lin H, Schonberger R. Opioid Dose Variation in Cardiac Surgery: A Multicenter Study of Practice. Anesthesia & Analgesia 2025, 140: 1016-1027. PMID: 39167548, PMCID: PMC11842693, DOI: 10.1213/ane.0000000000007128.Peer-Reviewed Original ResearchCardiac surgeryOpioid doseDose variationIntraoperative opioid administrationIntraoperative opioid doseHigh-dose opioidsAdult cardiac surgerySurgical differencesOpioid-freeOpioid administrationOpioid useMultimodal analgesiaAnalgesic techniquesCardiopulmonary bypassMulticenter studyFentanyl equivalentsSufentanil infusionSurgical patientsOpioidSurgeryAnesthetic techniqueCardiac casesAttending anesthesiologistPatientsDosePreoperative submaximal cardiopulmonary exercise testing and its association with early postoperative complications
Carr Z, Charchaflieh J, Brenes-Bastos A, He H, Lin H, Jankelovits A, Gu E, Zafar J, Ghali F, Tan W, Heerdt P. Preoperative submaximal cardiopulmonary exercise testing and its association with early postoperative complications. BJA Open 2025, 14: 100407. PMID: 40421445, PMCID: PMC12105740, DOI: 10.1016/j.bjao.2025.100407.Peer-Reviewed Original ResearchLength of staySubmaximal cardiopulmonary exercise testingInstitutional review board approvalPostoperative complication riskReview board approvalDuke Activity Status IndexCardiopulmonary exercise testingIncreased length of stayAdjusted multivariable regression modelsPostoperative complications predictionPulmonary capacitanceOpen-labelPeak oxygen uptakePerioperative surveillancePrimary endpointNoncardiac surgeryPostoperative complicationsSecondary endpointsSingle-centreComplication riskMET assessmentPeak VOBoard approvalMultivariate regression modelMetabolic equivalentsPost-transfusion activation of coagulation pathways during severe COVID-19 correlates with COVID-19 convalescent plasma antibody profiles
Weiss S, Lin H, Acosta E, Komarova N, Chen P, Wodarz D, Baine I, Duerr R, Wajnberg A, Gervais A, Bastard P, Casanova J, Arinsburg S, Swartz T, Aberg J, Bouvier N, Liu S, Alvarez R, Chen B. Post-transfusion activation of coagulation pathways during severe COVID-19 correlates with COVID-19 convalescent plasma antibody profiles. Journal Of Clinical Investigation 2025, 135: e181136. PMID: 40091845, PMCID: PMC11910229, DOI: 10.1172/jci181136.Peer-Reviewed Original ResearchConceptsCOVID-19 convalescent plasmaCOVID-19 convalescent plasma unitsActivation of coagulation pathwaysSevere COVID-19Post-transfusionAntibody profilesEffectiveness of COVID-19 convalescent plasmaSevere SARS-CoV-2 infectionCoagulation pathwayD-dimer levelsHospitalized COVID-19 patientsHigher-riskCCP recipientsSARS-CoV-2 infectionTreat severe COVID-19SARS-CoV-2 spikeCOVID-19 patientsAntibody therapyD-dimerD-dimer trendsConvalescent plasmaSevere diseaseBetacoronavirus OC43Higher mortalityIn vitro assaysBrain Signatures of Very Early Cognitive Decline in Asymptomatic Middle‐Aged Offspring of People With Alzheimer's Disease
Ramsingh N, Lin H, Ouyang Y, Ravona‐Springer R, Livny A, Soleimani L, Bendlin B, Matatov A, Niv T, Shamir T, Ganmore I, Heymann A, Sano M, Azuri J, Beeri M. Brain Signatures of Very Early Cognitive Decline in Asymptomatic Middle‐Aged Offspring of People With Alzheimer's Disease. International Journal Of Geriatric Psychiatry 2025, 40: e70060. PMID: 40050014, DOI: 10.1002/gps.70060.Peer-Reviewed Original ResearchConceptsSuperior longitudinal fasciculusCortical volumeCortical brain volumesWhite matterAlzheimer's Prevention studyEarly cognitive declineBrain signaturesBrain regionsCognitive changesWM microstructureMiddle-aged adultsBrain volumeLongitudinal fasciculusCognitive declinePreclinical cognitive changesOffspring of peopleBrain tractsPatient's offspringTarget individualsEarly interventionCorpus callosumParental historyBrainAlzheimer's diseaseLinear regression modelsPostoperative acute kidney injury is associated with persistent renal dysfunction: a multicentre propensity-matched cohort study
Stannard B, Epstein R, Gabel E, Nadkarni G, Ouyang Y, Lin H, Salari V, Hofer I. Postoperative acute kidney injury is associated with persistent renal dysfunction: a multicentre propensity-matched cohort study. BJA Open 2025, 14: 100384. PMID: 40129614, PMCID: PMC11930183, DOI: 10.1016/j.bjao.2025.100384.Peer-Reviewed Original ResearchPostoperative acute kidney injuryGlomerular filtration rateAcute kidney injuryRenal functionKidney injuryRates of postoperative acute kidney injuryOccurrence of postoperative acute kidney injuryAcute Kidney Injury Network classificationLong-term renal functionRetrospective propensity-matched studyCox modelPropensity-matched cohort studyPersistent renal dysfunctionIncreased hazardKaplan-Meier analysisFollow-up outpatient visitsFollow-up glomerular filtration ratePropensity-Matched StudyTertiary care hospitalHaemodialysis requirementRenal dysfunctionAdult patientsFiltration rateCohort studyHazard ratioThe role of right ventricular systolic pressure and ARISCAT score in perioperative pulmonary risk assessment
Tatsuoka Y, He Z, Lin H, Notarianni A, Carr Z. The role of right ventricular systolic pressure and ARISCAT score in perioperative pulmonary risk assessment. Brazilian Journal Of Anesthesiology 2025, 75: 844597. PMID: 39971234, PMCID: PMC11914786, DOI: 10.1016/j.bjane.2025.844597.Peer-Reviewed Original ResearchConceptsRight ventricular systolic pressurePostoperative pulmonary complicationsArea under the curveARISCAT scoreVentricular systolic pressureReceiver operating characteristic curvePulmonary hypertensionRespiratory failureHigh-risk populationPrimary endpointRisk stratificationSurgical proceduresSystolic pressurePostoperative pulmonary complications incidenceSource of increased morbidityAssess Respiratory RiskDiagnosis of PHPreoperative risk assessmentAdjusted multivariable logistic regression modelsMultivariate logistic regression modelComposite of pneumoniaPulmonary complicationsPreoperative investigationsSecondary endpointsPulmonary aspirationComparison of Perioperative Outcomes for Transfusion of Hemoconcentrated Bypass Versus Cell Saver Blood in Cardiac Surgical Patients
Bhatt H, Hu Y, Lin H, Egorova N, Ouyang Y, Levin M. Comparison of Perioperative Outcomes for Transfusion of Hemoconcentrated Bypass Versus Cell Saver Blood in Cardiac Surgical Patients. Journal Of Cardiothoracic And Vascular Anesthesia 2025, 39: 1173-1179. PMID: 39984367, DOI: 10.1053/j.jvca.2025.01.035.Peer-Reviewed Original ResearchConceptsCell saver bloodCardiac surgical patientsReduce transfusion ratesTransfusion rateIntensive care unitSurgical patientsPerioperative outcomesBlood productsTransfusion of packed red blood cellsElective open heart surgeryRed blood cell transfusionComparison of perioperative outcomesPostoperative blood transfusion ratePacked red blood cellsCase-control study SETTINGCell saver techniquesCell saver useBlood cell transfusionAtrial fibrillation historyBlood transfusion rateCardiac surgery patientsOff-pump casesRetrospective chart reviewFresh frozen plasmaHospital length of stay
2024
Individual and System-level Factors Contributing to Guideline Nonadherent Surgical Antibiotic Prophylaxis at a Tertiary Healthcare System: A Qualitative Analysis
Bardia A, Melnick E, McCall T, Zhao X, Lin H, Fisher C, Burg M, Schonberger R. Individual and System-level Factors Contributing to Guideline Nonadherent Surgical Antibiotic Prophylaxis at a Tertiary Healthcare System: A Qualitative Analysis. Anesthesiology 2024, 142: 489-499. PMID: 39556527, PMCID: PMC11813683, DOI: 10.1097/aln.0000000000005302.Peer-Reviewed Original ResearchClinical decision supportCertified Registered Nurse AnesthetistsGuideline adherenceInfectious Diseases Society of AmericaQualitative studyTertiary health care systemClinical decision support toolSemi-structured interview formatSystem-level factorsHealth care systemRegistered Nurse AnesthetistsConstant comparison methodInfectious Diseases SocietyDecision supportAntibiotic guidelinesCare systemProvider needsNurse anesthetistsPerioperative pharmacistLimited familiarityPerceived benefitsNon-adherenceInterview formatLevel factorsResident trainees
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