2025
B-cell infiltration distinguishes mucosal from skin patterns of rejection in facial vascularized composite allografts
Kauke-Navarro M, Crisler W, Younis N, Khetani R, Sadigh S, Teague J, Ho Sui S, Ko C, Zhan Q, Steuart S, Treister N, Pober J, Azzi J, Clark R, Pomahac B. B-cell infiltration distinguishes mucosal from skin patterns of rejection in facial vascularized composite allografts. American Journal Of Transplantation 2025 PMID: 39842779, DOI: 10.1016/j.ajt.2025.01.013.Peer-Reviewed Original ResearchFacial vascularized composite allotransplantationPeripheral blood mononuclear cellsB cell infiltrationB cellsMucosal rejectionRejection monitoringFacial vascularized composite allograftT cell-mediated rejectionSigns of immune activationNon-rejection biopsiesGranzyme B expressionB cell populationsInnate-like B cellsBlood mononuclear cellsVascularized composite allograftsVascularized composite allotransplantationAcute rejectionOral mucosaT cellsPattern of rejectionImmune activationMucosal biopsiesPlasma cellsSkin biopsiesMononuclear cells
2020
Mucosa and Rejection in Facial Vascularized Composite Allotransplantation: A Systematic Review.
Kauke M, Safi AF, Zhegibe A, Haug V, Kollar B, Nelms L, Palmer WJ, Tchiloemba B, Lian CG, Murphy GF, Pomahac B. Mucosa and Rejection in Facial Vascularized Composite Allotransplantation: A Systematic Review. Transplantation 2020, 104: 2616-2624. PMID: 32053572, DOI: 10.1097/tp.0000000000003171.Peer-Reviewed Original ResearchConceptsMucosal rejectionSystematic reviewRejection gradeMucosal biopsiesPatient managementComposite allotransplantationDiagnosis of rejectionFunction of patientsFacial Vascularized Composite AllotransplantationMeta-Analyses (PRISMA) guidelinesMEDLINE/PubMedPreferred Reporting ItemsVascularized Composite AllotransplantationPosttransplant periodBiopsy gradeSkin rejectionMucosa biopsiesAllograft skinAnimal studiesReporting ItemsBiopsyRejection processFacial allotransplantsMucosaTarget tissues
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