The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity
Nguyen N, Müller R, Briukhovetska D, Weber J, Feucht J, Künkele A, Hudecek M, Kobold S. The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity. Cancers 2024, 16: 2608. PMID: 39061247, PMCID: PMC11274444, DOI: 10.3390/cancers16142608.Peer-Reviewed Original ResearchCAR-T cellsLimitations of CAR-T cellsChimeric antigen receptor T cellsBiology of solid tumorsAdoptive cell therapyAnti-tumor immunityCo-stimulatory domainTransgenic cytokinesHLA incompatibilityMode of actionNK cellsHLA compatibilitySwitch receptorsDendritic cellsTumor microenvironmentHematologic neoplasiaT cellsHematological tumorsSolid tumorsImmune cellsAntigen presentationCell therapyCAR activationCellular vehiclesResponse rate
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