Nicholas Franco
Research Assistant PsychiatryDownloadHi-Res Photo
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Research Assistant II
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Research Assistant Psychiatry
Research Assistant II
Biography
Nicholas Franco has a background in Psychology. During his time at Yale he's worked under Dr. Krishnan-Sarin running various research studies with a focus on substance abuse. His recent work has included Mavoglurant and Saracatinib effects on alcohol drinking behaviors under the Center for the Translational Neuroscience of Alcoholism.
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Nicholas Franco's published research.
John Krystal, MD
Dana Cavallo, PhD
Jeanette Tetrault, MD, FACP, FASAM
Julia Shi, MD, FACP
Meghan Morean, PhD
Ralitza Gueorguieva, PhD
Publications
2019
Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial
Krishnan-Sarin S, O’Malley S, Franco N, Cavallo DA, Tetrault JM, Shi J, Gueorguieva R, Pittman B, Krystal JH. Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial. Neuropsychopharmacology 2019, 45: 319-326. PMID: 31590179, PMCID: PMC6901445, DOI: 10.1038/s41386-019-0536-z.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAlcohol drinking behaviorFirst treatment periodTreatment periodNumber of drinksCrossover trialDrinking behaviorEfficacy of naltrexoneOpioid antagonist naltrexoneNMDA antagonist memantinePositive family historyDay treatment periodSelf-administration periodAlcohol-induced stimulationAd lib accessMemantine treatmentAntagonist naltrexoneOpioid systemFamily historyNTXPriming drinkMemantineNaltrexoneAlcohol cravingHeavy drinkersAlcohol dependenceDoes Self-Reported or Behavioral Impulsivity Predict Subjective Response to Low-Dose Alcohol?
Berey BL, Leeman RF, Pittman B, Franco N, Krishnan-Sarin S. Does Self-Reported or Behavioral Impulsivity Predict Subjective Response to Low-Dose Alcohol? Alcohol And Alcoholism 2019, 54: 180-187. PMID: 30649160, PMCID: PMC6476413, DOI: 10.1093/alcalc/agy092.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLow-dose alcoholBlood alcohol concentrationAlcohol use disorderHeavy drinkersSubjective responsesTrend-level predictorNMDA receptor antagonistBiphasic Alcohol Effects ScaleAlcohol administration studyIndependent predictorsReceptor antagonistRisk factorsUse disordersSubjective stimulationGo/No-Go taskMore impulsive individualsHigh dosesEffects ScaleSedationAlcohol useSubjective effectsAdministration studiesImpulsivity measuresBarratt Impulsiveness ScaleDrinking occasions
2015
N‐Methyl‐d‐Aspartate Receptor Antagonism has Differential Effects on Alcohol Craving and Drinking in Heavy Drinkers
Krishnan‐Sarin S, O'Malley SS, Franco N, Cavallo DA, Morean M, Shi J, Pittman B, Krystal JH. N‐Methyl‐d‐Aspartate Receptor Antagonism has Differential Effects on Alcohol Craving and Drinking in Heavy Drinkers. Alcohol Clinical And Experimental Research 2015, 39: 300-307. PMID: 25664775, PMCID: PMC4331214, DOI: 10.1111/acer.12619.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAlcohol drinkingFamily historyHeavy drinkersAlcohol cravingN-methyl-D-aspartate receptor antagonistN-methyl-D-aspartate receptor antagonismAlcohol cue-induced cravingEffects of FHHigher baseline levelsPresence of impulsivityAlcohol use disorderCue-induced cravingAlcohol-induced stimulationReceptor antagonismReceptor antagonistPriming doseNMDA receptorsUse disordersMemantineBaseline levelsModulatory influencePotential efficacyAlcohol accessDrinkersEighth day