Saúl Rojas Sánchez, PhD
Associate Research ScientistCards
Appointments
Contact Info
About
Titles
Associate Research Scientist
Biography
Saúl Rojas Sánchez, Ph.D., is an Associate Research Scientist at the Yale School of Public Health in the Epidemiology of Microbial Diseases department. He received a Doctor of Philosophy degree in Experimental Biology and Biomedicine from the National Autonomous University of Mexico as part of the doctoral program of the Postgraduate School in Biological Sciences. During his undergraduate and graduate studies his research focused on the characterization of the specific DNA sequences responsible for promoting transcription of the U2 small nuclear RNA in the trypanosomatid parasite Leishmania major, which causes the disease known as leishmaniasis. The current studies of Dr. Saúl, conducted in the laboratory of Dr. Christian Tschudi, are focused toward understanding the molecular mechanisms causing gain of infectivity and quiescence in the protozoan parasite Trypanosoma brucei, the etiological agent of human and animal African trypanosomiasis.
Appointments
Therapeutic Radiology
Associate Research ScientistPrimary
Other Departments & Organizations
- All Institutions
- Escobar-Hoyos Lab
- Radiobiology
- Therapeutic Radiology
Education & Training
- PhD
- Universidad Nacional Autónoma de México (2016)
Research
Publications
2016
Molecular characterization of 5S ribosomal RNA genes and transcripts in the protozoan parasite Leishmania major.
Moreno-Campos R, Florencio-Martínez LE, Nepomuceno-Mejía T, Rojas-Sánchez S, Vélez-Ramírez DE, Padilla-Mejía NE, Figueroa-Angulo E, Manning-Cela R, Martínez-Calvillo S. Molecular characterization of 5S ribosomal RNA genes and transcripts in the protozoan parasite Leishmania major. Parasitology 2016, 143: 1917-1929. PMID: 27707420, DOI: 10.1017/S0031182016001712.Peer-Reviewed Original ResearchTranscription of Leishmania major U2 small nuclear RNA gene is directed by extragenic sequences located within a tRNA-like and a tRNA-Ala gene.
Rojas-Sánchez S, Figueroa-Angulo E, Moreno-Campos R, Florencio-Martínez LE, Manning-Cela RG, Martínez-Calvillo S. Transcription of Leishmania major U2 small nuclear RNA gene is directed by extragenic sequences located within a tRNA-like and a tRNA-Ala gene. Parasites & Vectors 2016, 9: 401. PMID: 27430335, PMCID: PMC4950102, DOI: 10.1186/s13071-016-1682-3.Peer-Reviewed Original Research
2015
BRF1, a subunit of RNA polymerase III transcription factor TFIIIB, is essential for cell growth of Trypanosoma brucei.
Vélez-Ramírez DE, Florencio-Martínez LE, Romero-Meza G, Rojas-Sánchez S, Moreno-Campos R, Arroyo R, Ortega-López J, Manning-Cela R, Martínez-Calvillo S. BRF1, a subunit of RNA polymerase III transcription factor TFIIIB, is essential for cell growth of Trypanosoma brucei. Parasitology 2015, 142: 1563-73. PMID: 26337955, DOI: 10.1017/S0031182015001122.Peer-Reviewed Original Research