A Randomized Trial of Three Routes of Tranexamic Acid Administration in Total Knee Arthroplasty.
Hootsmans N, Vellanky S, Grady-Benson J, Cremins M. A Randomized Trial of Three Routes of Tranexamic Acid Administration in Total Knee Arthroplasty. Orthopedics 2023, 46: 285-290. PMID: 36853950, DOI: 10.3928/01477447-20230224-04.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdministration, TopicalAntifibrinolytic AgentsArthroplasty, Replacement, KneeBlood Loss, SurgicalHemoglobinsHumansTranexamic AcidConceptsOral tranexamic acidTotal knee arthroplastyTopical TXA groupBlood transfusion rateTranexamic acidRoute of administrationTransfusion rateBlood lossChi-square testTXA administrationTXA groupKnee arthroplastyHemoglobin lossExact testPrimary total knee arthroplastySimilar clinical benefitsTranexamic acid administrationCalculated blood lossPearson's chi-square testFisher's exact testEase of administrationPerioperative bleedingBlood transfusionPrimary outcomeRandomized study
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