Varvara Nikolopoulou
she/her/hers
Postdoctoral AssociateDownloadHi-Res Photo
About
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Postdoctoral Associate
Biography
Varvara Nikolopoulou earned her Ph.D. in Analytical Chemistry from the National and Kapodistrian University of Athens, where she developed advanced analytical methodologies for detecting and characterizing emerging contaminants in complex environmental samples. Her research integrated novel non-target screening approaches, utilizing high-resolution mass spectrometry to uncover unknown contaminants and assess their impact on ecosystems. This work significantly advanced the understanding of the environmental fate and behavior of emerging contaminants, providing critical insights for regulatory and mitigation efforts.
Currently, Dr. Nikolopoulou is a Postdoctoral Associate at Yale University, where she is expanding her expertise in exposomics. She is particularly interested in leveraging advanced analytical techniques, such as trapped ion mobility spectrometry (TIMS) and MALDI-HRMS, to detect exposures and endogenous chemicals in biological samples. Her work incorporates spatialomics to achieve high-resolution, spatially resolved insights into the distribution of chemical species within tissues. By combining these innovative technologies, Dr. Nikolopoulou aims to deepen understanding of chemical exposures and their biological impacts, driving new discoveries in environmental health sciences.
Dr. Nikolopoulou was selected to participate in the Environmental Leadership and Mentorship (ELM) program at Yale School of Environment, a competitive certificate program designed to foster leadership and mentorship skills among a select group of participants. This prestigious program is open to a limited number of PostDocs who demonstrate outstanding potential in environmental research and leadership.
Departments & Organizations
- All Institutions
- Yale School of Public Health
Education & Training
- PhD
- National and Kapodistrian University of Athens, Department of Chemistry, Laboratory of Analytical Chemistry (2023)
- MSc
- National and Kapodistrian University of Athens, Department of Chemistry, Laboratory of Analytical Chemistry (2018)
- BSc
- National and Kapodistrian University of Athens, Department of Chemistry (2016)
Research
Overview
Public Health Interests
Environmental Health
ORCID
0000-0001-7980-2142- View Lab Website
Vasiliou Lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Varvara Nikolopoulou's published research.
Publications Timeline
A big-picture view of Varvara Nikolopoulou's research output by year.
Akiko Iwasaki, PhD
Albert Ko, MD
Andreas Coppi
David Thompson
Emily Davidson
Gary Désir, MD
11Publications
5Citations
Publications
Featured Publications
TrendProbe: Time profile analysis of emerging contaminants by LC-HRMS non-target screening and deep learning convolutional neural network.
Nikolopoulou V, Aalizadeh R, Nika MC, Thomaidis NS. TrendProbe: Time profile analysis of emerging contaminants by LC-HRMS non-target screening and deep learning convolutional neural network. J Hazard Mater 2022, 428: 128194. PMID: 35033918, DOI: 10.1016/j.jhazmat.2021.128194.Peer-Reviewed Original ResearchFirst Novel Workflow for Semiquantification of Emerging Contaminants in Environmental Samples Analyzed by Gas Chromatography-Atmospheric Pressure Chemical Ionization-Quadrupole Time of Flight-Mass Spectrometry.
Aalizadeh R, Nikolopoulou V, Alygizakis NA, Thomaidis NS. First Novel Workflow for Semiquantification of Emerging Contaminants in Environmental Samples Analyzed by Gas Chromatography-Atmospheric Pressure Chemical Ionization-Quadrupole Time of Flight-Mass Spectrometry. Anal Chem 2022, 94: 9766-9774. PMID: 35760399, DOI: 10.1021/acs.analchem.2c01432.Peer-Reviewed Original ResearchA novel workflow for semi-quantification of emerging contaminants in environmental samples analyzed by LC-HRMS.
Aalizadeh R, Nikolopoulou V, Alygizakis N, Slobodnik J, Thomaidis NS. A novel workflow for semi-quantification of emerging contaminants in environmental samples analyzed by LC-HRMS. Anal Bioanal Chem 2022, 414: 7435-7450. PMID: 35471250, DOI: 10.1007/s00216-022-04084-6.Peer-Reviewed Original ResearchWide-scope target and suspect screening of emerging contaminants in sewage sludge from Nigerian WWTPs by UPLC-qToF-MS.
Nikolopoulou V, Ajibola AS, Aalizadeh R, Thomaidis NS. Wide-scope target and suspect screening of emerging contaminants in sewage sludge from Nigerian WWTPs by UPLC-qToF-MS. Sci Total Environ 2023, 857: 159529. PMID: 36270367, DOI: 10.1016/j.scitotenv.2022.159529.Peer-Reviewed Original ResearchDevelopment of Liquid Chromatographic Retention Index Based on Cocamide Diethanolamine Homologous Series (C(n)-DEA).
Aalizadeh R, Nikolopoulou V, Thomaidis NS. Development of Liquid Chromatographic Retention Index Based on Cocamide Diethanolamine Homologous Series (C(n)-DEA). Anal Chem 2022, 94: 15987-15996. PMID: 36347512, DOI: 10.1021/acs.analchem.2c02893.Peer-Reviewed Original ResearchScreening of legacy and emerging substances in surface water, sediment, biota and groundwater samples collected in the Siverskyi Donets River Basin employing wide-scope target and suspect screening.
Nikolopoulou V, Alygizakis NA, Nika MC, Oswaldova M, Oswald P, Kostakis M, Koupa A, Thomaidis NS, Slobodnik J. Screening of legacy and emerging substances in surface water, sediment, biota and groundwater samples collected in the Siverskyi Donets River Basin employing wide-scope target and suspect screening. Sci Total Environ 2022, 805: 150253. PMID: 34818787, DOI: 10.1016/j.scitotenv.2021.150253.Peer-Reviewed Original Research
2024
Network analysis to reveal the most commonly detected compounds in predator-prey pairs in freshwater and marine mammals and fish in Europe.
Alygizakis N, Kostopoulou N, Gkotsis G, Nika MC, Orfanioti A, Ng K, Bizani E, Nikolopoulou V, Badry A, Brownlow A, Centelleghe C, Chadwick EA, Ciesielski TM, Cincinelli A, Claßen D, Danielsson S, Dekker RWRJ, Duke G, Glowacka N, Gol'din P, Jansman HAH, Jauniaux T, Knopf B, Koschorreck J, Krone O, Lekube X, Martellini T, Movalli P, O'Rourke E, Oswald P, Oswaldova M, Saavedra C, Persson S, Rohner S, Roos A, Routti H, Schmidt B, Sciancalepore G, Siebert U, Treu G, van den Brink NW, Vishnyakova K, Walker LA, Thomaidis NS, Slobodnik J. Network analysis to reveal the most commonly detected compounds in predator-prey pairs in freshwater and marine mammals and fish in Europe. Sci Total Environ 2024, 950: 175303. PMID: 39127197, DOI: 10.1016/j.scitotenv.2024.175303.Peer-Reviewed Original Research
2023
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model
Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan W, Davidson E, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder E, Coppi A, Schulz W, Iwasaki A, Pierce R, Cruz C, Desir G, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis N, Ko A, Thompson D, Vasiliou V. An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model. Human Genomics 2023, 17: 80. PMID: 37641126, PMCID: PMC10463861, DOI: 10.1186/s40246-023-00521-4.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCOVID-19 patientsDisease severityViral outbreaksFuture viral outbreaksLength of hospitalizationIntensive care unitWorse disease prognosisLife-threatening illnessEffective medical interventionsCOVID-19Clinical decision treeGlucuronic acid metabolitesNew potential biomarkersHospitalization lengthCare unitComorbidity dataSerotonin levelsDisease progressionHealthy controlsPatient outcomesDisease prognosisPatient transferPatientsHealthcare resourcesPotential biomarkers
2022
Assessment of contaminants of emerging concern in European apex predators and their prey by LC-QToF MS wide-scope target analysis.
Gkotsis G, Nika MC, Nikolopoulou V, Alygizakis N, Bizani E, Aalizadeh R, Badry A, Chadwick E, Cincinelli A, Claßen D, Danielsson S, Dekker R, Duke G, Drost W, Glowacka N, Göckener B, Jansman HAH, Juergens M, Knopf B, Koschorreck J, Krone O, Martellini T, Movalli P, Persson S, Potter ED, Rohner S, Roos A, O' Rourke E, Siebert U, Treu G, van den Brink NW, Walker LA, Williams R, Slobodnik J, Thomaidis NS. Assessment of contaminants of emerging concern in European apex predators and their prey by LC-QToF MS wide-scope target analysis. Environ Int 2022, 170: 107623. PMID: 36379200, DOI: 10.1016/j.envint.2022.107623.Peer-Reviewed Original ResearchDetermination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS.
Androulakakis A, Alygizakis N, Gkotsis G, Nika MC, Nikolopoulou V, Bizani E, Chadwick E, Cincinelli A, Claßen D, Danielsson S, Dekker RWRJ, Duke G, Glowacka N, Jansman HAH, Krone O, Martellini T, Movalli P, Persson S, Roos A, O'Rourke E, Siebert U, Treu G, van den Brink NW, Walker LA, Deaville R, Slobodnik J, Thomaidis NS. Determination of 56 per- and polyfluoroalkyl substances in top predators and their prey from Northern Europe by LC-MS/MS. Chemosphere 2022, 287: 131775. PMID: 34509025, DOI: 10.1016/j.chemosphere.2021.131775.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
honor Full Scholarship for doctoral studies (GA no. 1352)
National AwardHellenic Foundation for Research and Innovation & General Secretariat for Research and TechnologyDetails09/01/2019Greece
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Yale School of Public Health
60 College st
New Haven , CT 06510
United States
Locations
Lab 508
Lab
Yale School of Public Health (LEPH)
60 College Street, Fl 5th floor, Rm 508
New Haven, CT 06510