Vikas Thondapu, MD, PhD
Hospital ResidentCards
About
Research
Publications
2024
Selective Use of CT Fractional Flow at a Large Academic Medical Center: Insights from Clinical Implementation after 1 Year of Practice.
Randhawa M, Takigami A, Thondapu V, Ranganath P, Zhang E, Parakh A, Goiffon R, Baliyan V, Foldyna B, Lu M, Tower-Rader A, Meyersohn N, Hedgire S, Ghoshhajra B. Selective Use of CT Fractional Flow at a Large Academic Medical Center: Insights from Clinical Implementation after 1 Year of Practice. Radiology Cardiothoracic Imaging 2024, 6: e230073. PMID: 38573127, PMCID: PMC11056747, DOI: 10.1148/ryct.230073.Peer-Reviewed Original ResearchConceptsRate of invasive coronary angiographyCoronary CTAInvasive coronary angiographyCoronary CT angiographyCT-FFR analysisPercutaneous coronary interventionHeart rate controlCT-FFRRetrospective observational studyFractional flow reserveCT angiographyDual-source coronary CT angiographyCT fractional flow reserveFlow reserveObservational studyCoronary bypass graftingEarly diastolic periodBeats per minuteCoronary angiographyPhysician's discretionChart reviewClinical outcomesBypass graftingCTA acquisitionAcademic medical center
2023
Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention
Araki M, Park S, Dauerman H, Uemura S, Kim J, Di Mario C, Johnson T, Guagliumi G, Kastrati A, Joner M, Holm N, Alfonso F, Wijns W, Adriaenssens T, Nef H, Rioufol G, Amabile N, Souteyrand G, Meneveau N, Gerbaud E, Opolski M, Gonzalo N, Tearney G, Bouma B, Aguirre A, Mintz G, Stone G, Bourantas C, Räber L, Gili S, Mizuno K, Kimura S, Shinke T, Hong M, Jang Y, Cho J, Yan B, Porto I, Niccoli G, Montone R, Thondapu V, Papafaklis M, Michalis L, Reynolds H, Saw J, Libby P, Weisz G, Iannaccone M, Gori T, Toutouzas K, Yonetsu T, Minami Y, Takano M, Raffel O, Kurihara O, Soeda T, Sugiyama T, Kim H, Lee T, Higuma T, Nakajima A, Yamamoto E, Bryniarski K, Di Vito L, Vergallo R, Fracassi F, Russo M, Seegers L, McNulty I, Park S, Feldman M, Escaned J, Prati F, Arbustini E, Pinto F, Waksman R, Garcia-Garcia H, Maehara A, Ali Z, Finn A, Virmani R, Kini A, Daemen J, Kume T, Hibi K, Tanaka A, Akasaka T, Kubo T, Yasuda S, Croce K, Granada J, Lerman A, Prasad A, Regar E, Saito Y, Sankardas M, Subban V, Weissman N, Chen Y, Yu B, Nicholls S, Barlis P, West N, Arbab-Zadeh A, Ye J, Dijkstra J, Lee H, Narula J, Crea F, Nakamura S, Kakuta T, Fujimoto J, Fuster V, Jang I. Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention. Nature Reviews Cardiology 2023, 21: 348-348. PMID: 38110566, DOI: 10.1038/s41569-023-00982-z.Peer-Reviewed Original ResearchBone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction
Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee I, Mentkowski K, Grune J, Schloss M, Honold L, Iwamoto Y, Zheng Y, Bredella M, Buckless C, Ghoshhajra B, Thondapu V, van der Laan A, Piek J, Niessen H, Pallante F, Carnevale R, Perrotta S, Carnevale D, Iborra-Egea O, Muñoz-Guijosa C, Galvez-Monton C, Bayes-Genis A, Vidoudez C, Trauger S, Scadden D, Swirski F, Moskowitz M, Naxerova K, Nahrendorf M. Bone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction. Nature Cardiovascular Research 2023, 2: 1277-1290. PMID: 38344689, PMCID: PMC10857823, DOI: 10.1038/s44161-023-00388-7.Peer-Reviewed Original ResearchMyocardial infarctionFatty acid metabolismHematopoietic stem cell homeostasisEmergency hematopoiesisStem cell homeostasisAcid metabolismHematopoietic progenitor proliferationBone marrow adipocytesInflammatory myeloid cellsMyeloid cell expansionHematopoietic progenitor cellsBone marrow adiposityMitochondrial metabolismMetabolic cuesFatty acid oxidationCell homeostasisProgenitor proliferationHematopoietic cellsMarrow adipocytesAdipocyte shrinkageRegional sympathectomyHeart failureCell expansionFl miceProgenitor cells
2022
Clinical characteristics, treatment and outcomes of patients with spontaneous renal artery dissections
Dicks AB, Elgendy IY, Thondapu V, Ghoshhajra B, Waller HD, Rubio M, Schainfeld RM, Weinberg I. Clinical characteristics, treatment and outcomes of patients with spontaneous renal artery dissections. Journal Of Nephrology 2022, 36: 377-384. PMID: 36178591, DOI: 10.1007/s40620-022-01444-4.Peer-Reviewed Original ResearchConceptsSpontaneous renal artery dissectionRenal artery dissectionArtery dissectionMedical therapyNatural historyOutcomes of patientsTertiary care centerTime of diagnosisAbsence of symptomsConclusionMost patientsBaseline characteristicsClinical characteristicsMost patientsPatient demographicsRenal functionSymptomatic patientsMedical chartsRetrospective reviewBenign courseClinical presentationTherapy utilizationResultsA totalMedical historyCare centerBilling codes432 Feasibility And Clinical Outcomes Of Integrating CT-derived Fractional Flow Reserve (FFRCT) Into Clinical Practice: Insights From A Large Academic Medical Center
Takigami A, Thondapu V, Ranganath P, Zhang E, Parakh A, Goiffon R, Baliyan V, Foldyna B, Lu M, Tower-Rader A, Meyersohn N, Hedgire S, Ghoshhajra B. 432 Feasibility And Clinical Outcomes Of Integrating CT-derived Fractional Flow Reserve (FFRCT) Into Clinical Practice: Insights From A Large Academic Medical Center. Journal Of Cardiovascular Computed Tomography 2022, 16: s15-s16. DOI: 10.1016/j.jcct.2022.06.037.Peer-Reviewed Original ResearchBioresorbable‐polymer Everolimus‐eluting Stents
Thondapu V, Sutherland N, Ford T, Claessen B, Dangas G, Barlis P. Bioresorbable‐polymer Everolimus‐eluting Stents. 2022, 341-349. DOI: 10.1002/9781119697367.ch32.Peer-Reviewed Original ResearchMature clinical dataPlatinum-chromium EESTarget lesion revascularisationTarget vessel failureAssociated adverse eventsCornerstone of managementPercutaneous coronary interventionCoronary artery diseaseSecond-generation stentsLesion revascularisationAdverse eventsArtery diseaseCoronary interventionMedical therapyStent thrombosisLeading causeClinical dataVessel healingGeneration stentsStentsGold standardDevice iterationsLower ratesContemporary gold standardVessel failureAtherogenesis and Inflammation
Shishikura D, Octavia Y, Hayat U, Thondapu V, Barlis P. Atherogenesis and Inflammation. 2022, 1-20. DOI: 10.1002/9781119697367.ch1.Peer-Reviewed Original ResearchLow-density lipoprotein particlesInflammatory cell accumulationCoronary imaging modalitiesType II activationReactive oxygen species formationAcute inflammationCardiovascular diseasePlaque progressionVulnerable plaquesAtherosclerotic plaquesFibrous capIntimal wallCell accumulationOxygen species formationHistological studyArterial wallLipoprotein particlesMultifaceted pathologyImaging modalitiesInflammationLipid poolAtherogenesisPlaquesRapid recruitmentRecent updatesDurable Polymer Everolimus Eluting Stents
Thondapu V, Dayawansa N, Claessen B, Dangas G, Barlis P. Durable Polymer Everolimus Eluting Stents. 2022, 329-340. DOI: 10.1002/9781119697367.ch31.Peer-Reviewed Original ResearchOptical coherence tomography in coronary atherosclerosis assessment and intervention
Araki M, Park SJ, Dauerman HL, Uemura S, Kim JS, Di Mario C, Johnson TW, Guagliumi G, Kastrati A, Joner M, Holm NR, Alfonso F, Wijns W, Adriaenssens T, Nef H, Rioufol G, Amabile N, Souteyrand G, Meneveau N, Gerbaud E, Opolski MP, Gonzalo N, Tearney GJ, Bouma B, Aguirre AD, Mintz GS, Stone GW, Bourantas CV, Räber L, Gili S, Mizuno K, Kimura S, Shinke T, Hong MK, Jang Y, Cho JM, Yan BP, Porto I, Niccoli G, Montone RA, Thondapu V, Papafaklis MI, Michalis LK, Reynolds H, Saw J, Libby P, Weisz G, Iannaccone M, Gori T, Toutouzas K, Yonetsu T, Minami Y, Takano M, Raffel OC, Kurihara O, Soeda T, Sugiyama T, Kim HO, Lee T, Higuma T, Nakajima A, Yamamoto E, Bryniarski KL, Di Vito L, Vergallo R, Fracassi F, Russo M, Seegers LM, McNulty I, Park S, Feldman M, Escaned J, Prati F, Arbustini E, Pinto FJ, Waksman R, Garcia-Garcia HM, Maehara A, Ali Z, Finn AV, Virmani R, Kini AS, Daemen J, Kume T, Hibi K, Tanaka A, Akasaka T, Kubo T, Yasuda S, Croce K, Granada JF, Lerman A, Prasad A, Regar E, Saito Y, Sankardas MA, Subban V, Weissman NJ, Chen Y, Yu B, Nicholls SJ, Barlis P, West NEJ, Arbab-Zadeh A, Ye JC, Dijkstra J, Lee H, Narula J, Crea F, Nakamura S, Kakuta T, Fujimoto J, Fuster V, Jang IK. Optical coherence tomography in coronary atherosclerosis assessment and intervention. Nature Reviews Cardiology 2022, 19: 684-703. PMID: 35449407, PMCID: PMC9982688, DOI: 10.1038/s41569-022-00687-9.Peer-Reviewed Original ResearchConceptsOptical coherence tomographyPercutaneous coronary interventionCoronary atherosclerosisCoronary interventionNon-obstructive coronary arteriesCoherence tomographyAcute coronary syndromeManagement of patientsLate stent thrombosisEssential diagnostic modalityCoronary syndromeOCT findingsClinical outcomesPlaque pathologyStent thrombosisCoronary arteryCoronary plaquesMyocardial infarctionPlaque destabilizationRapid progressionClinical significanceDiagnostic modalitiesAtherosclerosis assessmentAtherosclerosisVascular biologyNon-Newtonian Endothelial Shear Stress Simulation: Does It Matter?
Thondapu V, Shishikura D, Dijkstra J, Zhu SJ, Revalor E, Serruys PW, van Gaal WJ, Poon EKW, Ooi A, Barlis P. Non-Newtonian Endothelial Shear Stress Simulation: Does It Matter? Frontiers In Cardiovascular Medicine 2022, 9: 835270. PMID: 35497989, PMCID: PMC9046559, DOI: 10.3389/fcvm.2022.835270.Peer-Reviewed Original Research