Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
Koche R, Rodriguez-Fos E, Helmsauer K, Burkert M, MacArthur I, Maag J, Chamorro R, Munoz-Perez N, Puiggròs M, Dorado Garcia H, Bei Y, Röefzaad C, Bardinet V, Szymansky A, Winkler A, Thole T, Timme N, Kasack K, Fuchs S, Klironomos F, Thiessen N, Blanc E, Schmelz K, Künkele A, Hundsdörfer P, Rosswog C, Theissen J, Beule D, Deubzer H, Sauer S, Toedling J, Fischer M, Hertwig F, Schwarz R, Eggert A, Torrents D, Schulte J, Henssen A. Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma. Nature Genetics 2019, 52: 29-34. PMID: 31844324, PMCID: PMC7008131, DOI: 10.1038/s41588-019-0547-z.Peer-Reviewed Original ResearchMeSH KeywordsCarcinogenesisDNA, CircularExtrachromosomal InheritanceGene RearrangementGenome, HumanHumansNeuroblastomaOncogenesRecombination, GeneticTumor Cells, Cultured
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